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Special Report, Americas, Entertainment
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Lewontin's early work, pioneering studies of genetic variation in fruit flies, catapulted him to scientific prominence. In addition to discovering a technique for measuring the degree of variation within the DNA of apparently homogeneous species, he was among the first to suggest the application of game theory to evolutionary problems. Along with research in humans carried out at the same time by Harry Harris, Lewontin's work demonstrated that the amount of genetic variation in nature provided “the stuff of evolution” on which natural selection could operate. Lewontin's recent work makes use of techniques such as gel electrophoresis, immunology, protein fingerprinting, heat sensitivity, and DNA sequencing to characterize the genetic variation in natural populations of different species of organisms. Lewontin's laboratory has detected and measured the frequency of different alleles (forms of a gene that are responsible for hereditary variation) at a large number of gene loci in different organisms and is precisely characterizing the amount and kind of variation. In order to determine the forces controlling the variation, his team applies different experimental techniques both in the laboratory and in nature to measure natural selection, to determine how much migration occurs between populations, and to study the breeding structure of natural populations.




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